Title :
Hybrid laser-activatable gold nanorods-loaded hydrogels for photothermal applications
Author :
Matteini, P. ; Ratto, F. ; Rossi, Francesco ; Giambastiani, G. ; Luconi, L. ; Tiribilli, B. ; Dei, L. ; Caminati, G.
Author_Institution :
Ist. di Fis. Applicata Nello Carrara, Italian Nat. Res. Council - CNR, Sesto Fiorentino, Italy
Abstract :
Gold nanorods (GNRs) show enhanced absorption in the near infrared (NIR) region and can be conveniently employed for selective conversion of light into heat. We have succeeded in fabricating hybrid GNRs-polysaccharides composites in the form of semi-solid formulations, films or hydrogels, with good biocompatibility, enhanced stabilization in physiological environment and under laser irradiation and high versatility. Thanks to these properties, these materials are good candidates for applications in many biomedical methodologies including laser-mediated tissue repair and drug delivery. The present results are encouraging toward the development of a novel minimally-invasive technology based on the introduction of bio-inspired nanoplasmonic materials into photothermal applications.
Keywords :
biomedical materials; gold; hydrogels; laser materials processing; nanobiotechnology; nanofabrication; nanophotonics; nanorods; optical fabrication; optical films; optical polymers; Au; biocompatibility; bioinspired nanoplasmonic materials; drug delivery; hybrid laser-activatable gold nanorods; hybrid polysaccharide composites; hydrogels; laser irradiation; laser-mediated tissue repair; light-to-heat conversion; minimally-invasive technology; near infrared absorption; optical films; photothermal applications; physiological environment; semisolid formulations; Films; Gold; Laser applications; Laser stability; Nanobioscience; Nanoparticles;
Conference_Titel :
BioPhotonics, 2011 International Workshop on
Conference_Location :
Parma
Print_ISBN :
978-1-4244-9836-9
Electronic_ISBN :
978-1-4244-9835-2
DOI :
10.1109/IWBP.2011.5954855
