Ventricular wall bulge and oxygen consumption in stunned myocardium modeling

Author

Wang, Jia-Jung ; Drzewiecki, Gary ; Li, John K-J.

Author_Institution

Dept. of Biomed. Eng., Rutgers Univ., Piscataway, NJ, USA

fYear

1995

fDate

22-23 May 1995

Firstpage

7

Lastpage

9

Abstract

Reversible dysfunction of the myocardium after a single or multiple episodes of coronary artery occlusion is termed myocardial stunning. In this study, the hypothesis that stunning could best be represented by an increase in resting length and a concomitant decrease in maximum available muscle force in the stunned region was examined by means of a mathematical model. Hemodynamic measures were found to be similar to those of experiment data, thus supporting the model validity. Oxygen consumption was found to slightly increase as paradoxically observed in experiments. The model explains this as increased heat production while external work decreases with stunning

Keywords

biomechanics; cardiology; haemodynamics; muscle; oxygen; physiological models; O₂; coronary artery occlusion; external work; hemodynamic measures; increased heat production; mathematical model; maximum available muscle force decrease; model validity; myocardial stunning; oxygen consumption; resting length increase; stunned myocardium modeling; ventricular wall bulge; Analog circuits; Arterial occlusion; Biomedical engineering; Cardiology; Laboratories; Mathematical model; Muscles; Myocardium; Oxygen; Shape control;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioengineering Conference, 1995., Proceedings of the 1995 IEEE 21st Annual Northeast

Conference_Location

Bar Harbor, ME

Print_ISBN

0-7803-2692-X

Type

conf

DOI

10.1109/NEBC.1995.513712

Filename

513712