Title :
Study on some modeling problems in the process of gene expression with finite state machine
Author :
Gao, Rui ; Hu, Wensong
Author_Institution :
Sch. of Control Sci. & Eng., Shandong Univ., Ji´´nan, China
Abstract :
Finite state machine (FSM) theory has great potentialities in understanding key concepts and analyzing molecular biological systems, especially in the process of gene expression. Based on the previous research work, this paper extends the study on the control problems in metabolism and gene mutation with FSM. The goal is to interpret how to apply control technologies to process of metabolism, and how to eliminate the effects to secondary structures of protein caused by gene mutation. It is hoped that the proposed model-based analysis will provide an exploration of new interdisciplinary theories intersected by information science, control theory, and the Molecular Biology.
Keywords :
finite state machines; genetics; medical control systems; molecular biophysics; proteins; FSM theory; control problem; control technology; control theory; finite state machine; gene expression; gene mutation; information science; metabolism; model-based analysis; modeling problem; molecular biological system; protein; DNA; Hidden Markov models; Mathematical model; Matrix converters; Proteins; Radiation detectors; Control analysis; gene expression; gene mutation; metabolism;
Conference_Titel :
Intelligent Control and Automation (WCICA), 2012 10th World Congress on
Conference_Location :
Beijing
Print_ISBN :
978-1-4673-1397-1
DOI :
10.1109/WCICA.2012.6359438