Title :
Microelectronic channel bridge and signal regeneration of injured spinal cords
Author :
Wang, Zhi-Gong ; Gu, Xiao-Song ; Lü, Xiao-Ying ; Jiang, Zheng-Lin ; Li, Wen-Yuan ; Lü, Guang-Ming ; Wang, Yu-Feng ; Wang, Hui-Ling ; Zhang, Zhen-Yu ; Shen, Hong-Mei ; Wu, Yang ; Shen, Wei-Xing ; Zhang, Jing-Yang ; Chen, Dong
Author_Institution :
Inst. of RF- & OE-ICs, Southeast Univ., Nanjing
fDate :
Nov. 30 2008-Dec. 3 2008
Abstract :
We are searching for a way to generate neural function recovery by introducing an implantable microelectronic system. Prototypes of the so-called microelectronic neural-bridging systems have been realized in the form of integrated circuits. The integrated circuits were realized in a standard CMOS process. In a series of animal experiments, we have demonstrated that an interrupted spinal cord could be bridged and neural signals were regenerated. The idea of microelectronics channel bridging and signal regeneration of injured spinal cords was primarily demonstrated.
Keywords :
CMOS integrated circuits; bioelectric phenomena; biomedical electronics; neuromuscular stimulation; neurophysiology; wounds; CMOS process; implantable microelectronic system; injured spinal cords; integrated circuits; microelectronic channel bridging systems; neural function recovery; neural signal regeneration; Animals; Bridge circuits; Humans; Microelectronics; Nerve fibers; Nervous system; Radio frequency; Spinal cord; Spinal cord injury; Stem cells;
Conference_Titel :
Circuits and Systems, 2008. APCCAS 2008. IEEE Asia Pacific Conference on
Conference_Location :
Macao
Print_ISBN :
978-1-4244-2341-5
Electronic_ISBN :
978-1-4244-2342-2
DOI :
10.1109/APCCAS.2008.4746109