Title :
Terahertz time-domain spectroscopy of peptides in solution
Author :
Li, R. ; Ding, T. ; Huber, T. ; Falconer, R.J. ; Middelberg, A.P.J. ; Gladden, L.F. ; Zeitler, J.A.
Author_Institution :
Dept. of Chem. Eng. & Biotechnol., Univ. of Cambridge, Cambridge, UK
Abstract :
The terahertz absorption spectra of different peptides in buffer solutions were measured in the frozen state (80 K) with different peptide concentrations. The observed absorption peaks, confirmed by independent measurement at the Australian synchrotron, are believed to directly relate to the formation of KF crystals upon freezing. This process is significantly suppressed by including peptide in the buffer.
Keywords :
biological techniques; molecular biophysics; terahertz spectroscopy; terahertz wave spectra; Australian synchrotron; KF crystal formation; absorption peaks; buffer solutions; solution phase peptides; temperature 80 K; terahertz absorption spectra; terahertz time domain spectroscopy; Absorption; Amino acids; Australia; Chemical engineering; Peptides; Proteins; Spectroscopy; Submillimeter wave measurements; Synchrotrons; Time domain analysis;
Conference_Titel :
Infrared, Millimeter, and Terahertz Waves, 2009. IRMMW-THz 2009. 34th International Conference on
Conference_Location :
Busan
Print_ISBN :
978-1-4244-5416-7
Electronic_ISBN :
978-1-4244-5417-4
DOI :
10.1109/ICIMW.2009.5325615
