Title :
Kinetic release of levodopa from Zn/Al-layered double hydroxide host
Author :
Hussein, Mohd Zobir ; Ghani, Sarinawani Abdul ; Abdullah, A.H.
Author_Institution :
Adv. Mater. & Nanotechnol. Lab., Univ. Putra Malaysia, Serdang, Malaysia
Abstract :
Kinetic release of Levodopa from Zn/Al-layered double hydroxide host is reported. The levodopa (LD) is an organic guest, is intercalated into the Zn-Al-layered double hydroxide lamella and was synthesized using direct co-precipitation method at pH 7.5 and Zn to Al molar ratio of 4, aged for 18 h at 70 οC. Release study of the levodopa from nanohybrid into various concentrations of sodium carbonate and sodium chloride solutions was studied using uv-visible spectroscopic method.
Keywords :
aluminium compounds; biomedical materials; intercalation compounds; nanobiotechnology; nanocomposites; nanofabrication; organic compounds; organic-inorganic hybrid materials; pH; precipitation; spectrochemical analysis; ultraviolet spectra; visible spectra; zinc compounds; 3-(3,4-dihydroxyphenil)-L-alanine; UV-visible spectroscopy; Zn(OH)2-Al(OH)3; direct coprecipitation method; drug delivery; intercalation compounds; layered double hydroxide host; levodopa; organic-inorganoc hybrid type nanolayered composites; pH; sodium carbonate solution; sodium chloride solution;
Conference_Titel :
Enabling Science and Nanotechnology (ESciNano), 2010 International Conference on
Conference_Location :
Kuala Lumpur
Print_ISBN :
978-1-4244-8853-7
DOI :
10.1109/ESCINANO.2010.5700963
