Title :
Fabrication and application of nanofork for measuring single cells adhesion force inside ESEM
Author :
Ahmad, Mohd Ridzuan ; Nakajima, Masahiro ; Kojima, Masaru ; Kojima, Seiji ; Homma, Michio ; Fukuda, Toshio
Author_Institution :
Mater. Innovations & Nanoelectron. Res. Group, Univ. Teknol. Malaysia, Skudai, Malaysia
Abstract :
In this paper, a new strategy is proposed for measuring the cell adhesion force by using a nanofork and a line-patterned substrate. The nanofork has three tines which resembles the appearance of a normal fork. In order to effectively implement the nanofork, a special design substrate, known as line-patterned (LP) substrate, is required. The spaces between the line structures on the substrate provide gaps between the cells and the substrate.
Keywords :
adhesion; biological techniques; biomechanics; force measurement; nanobiotechnology; nanofabrication; nanostructured materials; ESEM; line-patterned substrate; nanofork; single cells adhesion force;
Conference_Titel :
Enabling Science and Nanotechnology (ESciNano), 2010 International Conference on
Conference_Location :
Kuala Lumpur
Print_ISBN :
978-1-4244-8853-7
DOI :
10.1109/ESCINANO.2010.5700976
