Title :
α-surface and its application to mining protein data
Author_Institution :
Dept. of Comput. Sci., California State Univ., Fullerton, CA, USA
Abstract :
Given a finite set of points in three dimensional Euclidean space R3, the subset that forms its surface could be different when observed at different levels of detail. In this paper we introduce a notion called α-surface. We present an algorithm that extracts the α-surface from a finite set of points in R3. We apply the algorithm to extracting the α-surfaces of proteins and discover patterns from these surface structures using a pattern discovery algorithm. We then use these patterns to classify the proteins. Experimental results demonstrate the good performance of the proposed approach
Keywords :
biology computing; data mining; molecular biophysics; pattern classification; proteins; α-surface extraction algorithm; 3D Euclidean space; finite points set; pattern discovery; protein classification; protein data mining; surface structures; Application software; Classification algorithms; Computer science; Data mining; Euclidean distance; Protein engineering;
Conference_Titel :
Data Mining, 2001. ICDM 2001, Proceedings IEEE International Conference on
Conference_Location :
San Jose, CA
Print_ISBN :
0-7695-1119-8
DOI :
10.1109/ICDM.2001.989598