Parameter Extraction for Neuron Model Simulation of Action Potential in Earthworm Giant Nerve Fiber

Author

Deka, Rashmi ; Dutta, Jiten C.

Author_Institution

Dept. of Electron. & Commun. Eng., Tezpur Univ., Tezpur, India

fYear

2015

fDate

13-14 Feb. 2015

Firstpage

732

Lastpage

736

Abstract

Proper modeling of neuron plays an important role in biophysical description of action potential of nerve fibers. Measurement in giant axon has historical importance as squid giant axon was used extensively for voltage clamp experiments performed by Hodgkin and Huxley in 1952. This paper presents the application of Graphical User Interface (GUI) in MATLAB in extracting parameters for neuron modeling. The model parameters are determined based on the measurement of action potential in earthworm giant nerve fiber with the help of Power Lab 4/25T supplied by ADINSTRUMENTS.

Keywords

graphical user interfaces; neurophysiology; ADInstruments; GUI; Matlab; PowerLab 4/25T; biophysical description; earthworm giant-nerve fiber; graphical user interface; neuron model action potential measurement; neuron model simulation; parameter extraction; squid giant axon; voltage clamp experiments; Biological system modeling; Biomembranes; Electric potential; Equations; Graphical user interfaces; Mathematical model; Nerve fibers; GUI; Modeling; Power Lab 4/25T; action potential; axon;

fLanguage

English

Publisher

ieee

Conference_Titel

Computational Intelligence & Communication Technology (CICT), 2015 IEEE International Conference on

Conference_Location

Ghaziabad

Print_ISBN

978-1-4799-6022-4

Type

conf

DOI

10.1109/CICT.2015.57

Filename

7078799