Title :
Fabrication of a flexible neural interface device with CMOS-based smart electrodes
Author :
Noda, Toshihiko ; Kitao, Takuya ; Ito, Takasuke ; Sasagawa, Kiyotaka ; Tokuda, Takashi ; Terasawa, Yasuo ; Tashiro, Hiroyuki ; Kanda, Hiroyuki ; Fujikado, Takashi ; Ohta, Jun
Author_Institution :
Grad. Sch. of Mater. Sci., Nara Inst. of Sci. & Technol., Ikoma, Japan
Abstract :
A novel flexible neural interface device was proposed, designed and fabricated. The device realizes electrical stimulation and measurement of neural tissues using an array of smart electrodes. The smart electrode has intelligence by dedicated CMOS microchip. Thanks to the smart electrodes high functions of the array with large number of electrodes are obtained only with 4 wiring connected to external equipments. Moreover, the device has enough flexibility for low invasion to the living body tissues. As one of in vivo evaluations, retinal stimulation was performed with the device using an experimental animal. Stimulus function of the device implanted into the living body was demonstrated successfully, responses caused by the stimulation were observed.
Keywords :
CMOS integrated circuits; bioMEMS; biological tissues; biomedical measurement; electrodes; microfabrication; CMOS microchip; CMOS-based smart electrodes; MEMS technology; electrical measurement; electrical stimulation; flexible neural interface device fabrication; in vivo evaluations; living body tissues; neural tissues; retinal stimulation; Arrays; CMOS integrated circuits; Electric potential; Electrodes; Performance evaluation; Retina; Substrates; CMOS; flexible device; neural interface; retinal stimulation; smart electrode;
Conference_Titel :
VLSI and System-on-Chip (VLSI-SoC), 2011 IEEE/IFIP 19th International Conference on
Conference_Location :
Hong Kong
Print_ISBN :
978-1-4577-0171-9
Electronic_ISBN :
978-1-4577-0169-6
DOI :
10.1109/VLSISoC.2011.6081608
