Title :
Development of continuous detectors for a high resolution animal PET system
Author :
Siegel, Stefan ; Cherry, Simon R. ; Ricci, Anthony R. ; Shao, Yiping ; Phelps, Michael E.
Author_Institution :
Sch. of Med., California Univ., Los Angeles, CA, USA
fDate :
30 Oct-5 Nov 1994
Abstract :
We propose a design for high resolution, gamma camera style detectors suitable for use in a positron emission tomograph dedicated to small animal research. Through calculation and Monte Carlo simulation we model the performance of a detector comprised of a 76.2×76.2×8 mm thick LSO crystal coupled to a 3" square position sensitive photomultiplier tube (PS-PMT). We investigated the effect of optical coupling compounds, surface treatment and depth of interaction on the quantity (efficiency) and distribution (spread) of scintillation photons reaching the photocathode. We also investigated linearization of the position response and describe an algorithm for determining the loss in system spatial resolution due to depth of interaction effects. We propose a PET system consisting of fourteen of these detectors in 2 rings, yielding a 16 cm Ø by 15 cm long tomograph. It would operate in 3-D mode subtending a 68% solid angle to the center. The expected spatial resolution is ⩽2 mm, with a system efficiency of ~10% (200 keV lower threshold) and a singles count rate capability of 8×106 cps per detector
Keywords :
Monte Carlo methods; biomedical equipment; gamma-ray detection; image resolution; photomultipliers; position sensitive particle detectors; positron emission tomography; solid scintillation detectors; 10 percent; 15 cm; 16 cm; 200 keV; 3 in; 3-D mode; 76.2 mm; 8 mm; LSO crystal; Monte Carlo simulation; continuous detectors; depth of interaction; design; efficiency; high resolution animal PET system; high resolution gamma camera style detectors; linearization; optical coupling compounds; photocathode; position sensitive photomultiplier tube; positron emission tomograph; quantity; scintillation photons; singles count rate capability; small animal research; spatial resolution; surface treatment; system efficiency; Animals; Cameras; Gamma ray detection; Gamma ray detectors; Photomultipliers; Photonic crystals; Position sensitive particle detectors; Radioactive decay; Solid scintillation detectors; Spatial resolution;
Conference_Titel :
Nuclear Science Symposium and Medical Imaging Conference, 1994., 1994 IEEE Conference Record
Conference_Location :
Norfolk, VA
Print_ISBN :
0-7803-2544-3
DOI :
10.1109/NSSMIC.1994.474744
