Title :
1G-3 HF Ultrasound Device Designed to Describe the Whole Blood Coagulation Process: Application to Rats under Anticoagulant Therapy
Author :
Libgot, R. ; Ossant, F. ; Desbuards, N. ; Rochefort, G.Y. ; Antier, D. ; Gruel, Y. ; Patat, F.
Author_Institution :
Univ. Francois Rabelais, CNRS, Tours
Abstract :
In previous studies [Ossant, et. al., 2004; Libgot, et. al., 2005], we presented a device capable to simultaneously estimate, during the blood clotting process, HF ultrasound parameters both in double-transmission mode (DT-mode) and in backscattering mode (BS-mode). The integrated BS coefficient (IBC) and the effective scatterer size (ESS) were evaluated between 10 and 30 MHz. In DT-mode, sound velocity was estimated with a 45 MHz transducer. The aim of the present work was to confirm several specific results with human whole blood and to validate the method with an animal model: the rat under anticoagulant therapy. Acoustic velocity was estimated during ex-vivo coagulation process of blood from heparin-treated rats
Keywords :
biomedical ultrasonics; blood; coagulation; ultrasonic transducers; ultrasonic velocity; 45 MHz; HF ultrasound device; acoustic velocity; anticoagulant therapy; backscattering; blood clotting; blood coagulation; heparin; rats; ultrasonic transducers; Acoustic scattering; Acoustic transducers; Backscatter; Blood; Coagulation; Electronic switching systems; Hafnium; Medical treatment; Rats; Ultrasonic imaging;
Conference_Titel :
Ultrasonics Symposium, 2006. IEEE
Conference_Location :
Vancouver, BC
Print_ISBN :
1-4244-0201-8
Electronic_ISBN :
1051-0117
DOI :
10.1109/ULTSYM.2006.167
