P1B-2 In-Vivo Exploration of the Mechanical Properties of Healthy and Pathological Human Dermis with 2D High Resolution Elastography

This work was based on 2D high frequency elastography used to describe, quantitatively, the mechanical behavior of human dermis in vivo in terms of axial strain and lateral displacement. The experiment material was the combination of 2 devices. First, an extensiometer developed by LMARC laboratory for in-vivo skin applications using uniaxial stretching stress. Second, our 20 MHz real time sonographer, Dermcup 2020trade. Filtered and Staggered Strain Estimation algorithm (SSE + low-pass filtering), was used to produce elastograms. A temporal cumulative technique was applied and kinetics of the axial strain, epsiv(t), and lateral retraction were obtained for homogeneous ROIs in the dermis. Kinetic profiles were useful to study several characteristics: inter-individual variations, viscoelasticity and reproducibility. Results on pathological dermis were discussed in the conclusion