DocumentCode
2355677
Title
Analysis of the hot spots of coated pits in live cells
Author
Deng, Jia ; Leung, Henry ; Elliott, Robert J. ; Wong, Stephen ; Zhou, Xiaobo
Author_Institution
Calgary Univ., Calgary
fYear
2007
fDate
8-9 Nov. 2007
Firstpage
51
Lastpage
54
Abstract
Coated pits carry important information about plasma membrane and endosomes. They remove proteins and lipids from the plasma membrane and transport them to the endosomal compartment. It is of interest to get a thorough understanding of these pits. In this paper, we consider two kinds of proteins in coated pits: clathrin and AP-2. We propose a detection method to extract as many coated pits trajectories as possible. It is observed that we can predict whether or not a pit will appear at certain "hot spot" at a certain time.
Keywords
biomembrane transport; lipid bilayers; molecular biophysics; proteins; AP-2 proteins; clathrin proteins; coated pits; endosomes; hot spots; lipids; live cells; plasma membrane; Biomedical engineering; Biomembranes; Educational institutions; Hospitals; Information analysis; Lipidomics; Motion pictures; Plasma transport processes; Proteins; Radiology;
fLanguage
English
Publisher
ieee
Conference_Titel
Life Science Systems and Applications Workshop, 2007. LISA 2007. IEEE/NIH
Conference_Location
Bethesda, MD
Print_ISBN
978-1-4244-1813-8
Electronic_ISBN
978-1-4244-1813-8
Type
conf
DOI
10.1109/LSSA.2007.4400882
Filename
4400882
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