Title :
SPICE and difference equations for modelling the binding, dissociation, and internalization of EGF
Author :
Prideaux, Jeff ; Mikulecky, Donald ; Ware, Joy
Author_Institution :
Dept. of Physiol., MCV/VCU, Richmond, VA, USA
Abstract :
The authors compare expressing the differential equations for the binding, dissociation, and internalization of EGF (epidermal growth factor) as difference equations and as an electronic circuit using the electronic simulation package SPICE. Both approaches yielded identical results and suggest fruitful methods for examining physiological processes
Keywords :
SPICE; difference equations; organic compounds; physiological models; skin; binding; dissociation; electronic circuit; electronic simulation package; epidermal growth factor; internalization; physiological processes; Biological system modeling; Circuit simulation; Computational modeling; Computer simulation; Difference equations; Differential equations; Kinematics; Pathology; Physiology; SPICE;
Conference_Titel :
Engineering in Medicine and Biology Society, 1994. Engineering Advances: New Opportunities for Biomedical Engineers. Proceedings of the 16th Annual International Conference of the IEEE
Conference_Location :
Baltimore, MD
Print_ISBN :
0-7803-2050-6
DOI :
10.1109/IEMBS.1994.415267
