Title :
Analysis of the noise associated to the muscarinic modulation of the mouse perirhinal cortex
Author :
Spaiardi, Paolo ; Talpo, Francesca ; Toselli, Mauro ; Biella, Gerardo ; Marinoni, Andrea ; Savazzi, Pietro ; Favalli, Lorenzo
Author_Institution :
Dept. of Physiol. Sci., Univ. of Pavia, Pavia, Italy
Abstract :
The perirhinal cortex (PRC) is a polymodal associative area which plays a key role in several memory processes. It has been shown that cholinergic muscarinic modulation plays a crucial role in regulating PRC functions. In this work, changes in the signal noise during muscarinic modulation of the PRC have been observed and analyzed. The relationship between these changes and the information processing performed by neurons of the PRC are inevstigated. In more details, the effects of muscarinic modulation on the membrane potential and on the voltage membrane noise of pyramidal neurons and GABAergic interneurons are inevstigated, both from deep and superficial layers of the PRC.
Keywords :
bioelectric potentials; brain; cellular biophysics; medical signal processing; neurophysiology; random noise; GABAergic interneurons; PRC function regulation; cholinergic muscarinic modulation; membrane potential; memory processes; mouse PCR muscarinic modulation associated noise; mouse perirhinal cortex; neuron information processing; noise analysis; polymodal associative area; pyramidal neurons; signal noise changes; voltage membrane noise; mus-carinic modulation; noise analysis; perirhinal cortex;
Conference_Titel :
Applied Sciences in Biomedical and Communication Technologies (ISABEL), 2010 3rd International Symposium on
Conference_Location :
Rome
Print_ISBN :
978-1-4244-8131-6
DOI :
10.1109/ISABEL.2010.5702765
