New recording setup for ratiometric recording of action potentials by optical means

Author

Bardonova, J. ; Provaznik, I. ; Novakova, M. ; Nogova, K. ; Sekora, J.

Author_Institution

Brno Univ. of Technol., Brno

fYear

2008

fDate

14-17 Sept. 2008

Firstpage

1085

Lastpage

1088

Abstract

Monophasic action potential (MAP) can be recorded from the heart surface by optical method via fluorescence measurement. The motion of isolated heart during experiment caused additional noise in recorded signal. The motion artifact can be eliminated by ratiometric fluorescence emission measurements. This study is based on experiments in which a new ratiometric recording setup is used for recording MAPs from isolated rabbit hearts perfused according to Langendorff. MAPs recorded by new ratiometric recording setup are compared with simple optical MAP measurement without ratiometry.

Keywords

bioelectric potentials; cardiovascular system; fluorescence; haemorheology; medical signal processing; Langendorff method; heart surface; isolated heart motion; isolated rabbit heart perfusion; monophasic action potential; motion artifact; optical method; ratiometric fluorescence emission measurements; ratiometric recording; ratiometric recording setup; recorded noise signal; Fluorescence; Heart; Optical noise; Optical recording; Optical sensors; Optical surface waves; Rabbits; Stimulated emission; Voltage; Wavelength measurement;

fLanguage

English

Publisher

ieee

Conference_Titel

Computers in Cardiology, 2008

Conference_Location

Bologna

ISSN

0276-6547

Print_ISBN

978-1-4244-3706-1

Type

conf

DOI

10.1109/CIC.2008.4749234

Filename

4749234