Smart-drug delivery system employing molecular motors

A drug delivery system has been envisioned employing actinmyosin molecular motors, liposomes, microcantilevers and a specific track formed by microfilaments. Molecular motors can pull on giant liposomes enclosing the drug to be delivered at the target site. An array of microcantilevers whose deflection in nanometers would cause the opening of the valves responsible for delivering the drug, would be implanted within the liposomes. A particular microfilament network would be designed to provide direction to the molecular motors carrying the liposomes towards the specific target site, where specific biochemical recognition occurs between the immobilized biomolecules adsorbed on the microcantilever surface and the complementary disease biomarkers. The formation of complexes between the complementary biomolecules deflects the microcantilevers causing the opening of the valves, which release the drug at the particular target site.