The Application of Micro-Plate Dynamics on Monitoring Cell Property

The paper presents a novel biosensing method of monitoring cell properties using the information derived from the dynamics of micro scale plates. Micro cantilevers have been widely applied as mechanical biosensors. In dynamics sense, cantilever is considered as 1 dimensional whereas plate is a 2 dimensional structure. In this paper we provide the first analytical solution to the dynamics of distributed mass loaded microplate in submerged fluid. In a further step, we propose to derive the dynamical information of the micro plate and use it to infer the spatial information of the cells when monitoring the cell growth on the plate.