Title :
Quantitative determination of cardiac function based on 3-D geometrical analysis
Author :
Sideman, S. ; Azhari, A. ; Bayar, R. ; Dinnar, U. ; Wang, J.Z. ; Mezrich, R. ; Welkowitz, W.
Author_Institution :
Dept. of Biomed. Eng., Rutgers Univ., Piscataway, NJ, USA
Abstract :
A novel ventricular analytical procedure for 3-D reconstruction of the left ventricle (LV) is utilized to define quantitatively the 3-D shape by a size-independent individual geometric cardiogram (GCG). Individual vectors can then be grouped to define the characteristic shape of the normal heart and the pathological state. Shape, wall thickness, and stress were found to be sensitive to regional infarction. Magnetic resonance image (MRI) data of ischemic dogs and cine-computed tomography analysis of patients with clinically defined diseased LV verify the power of this procedure to identify pathological shape changes. The convenient application of shape analysis is demonstrated by MRI studies of hypertrophy under hypotension for a period of 23 weeks
Keywords :
biomechanics; biomedical NMR; cardiology; computerised tomography; 3D geometrical analysis; 3D reconstruction; 3D shape; MRI; cardiac function; characteristic shape; cine-computed tomography analysis; clinically defined diseased LV; hypertrophy; hypotension; ischemic dogs; left ventricle; magnetic resonance image data; normal heart; pathological state; quantitative determination; regional infarction; size-independent individual geometric cardiogram; stress; vectors; ventricular analytical procedure; wall thickness; Cardiology; Dogs; Heart; Magnetic analysis; Magnetic resonance; Magnetic resonance imaging; Pathology; Shape; Stress; Three dimensional displays;
Conference_Titel :
Bioengineering Conference, 1989., Proceedings of the 1989 Fifteenth Annual Northeast
Conference_Location :
Boston, MA
DOI :
10.1109/NEBC.1989.36674
