Title :
A simple model of the chemical regulation of acid-base balance in blood
Author :
Chiari, L. ; Avanzolini, G. ; Grandi, F. ; Gnudi, G.
Author_Institution :
Dipartimento di Elettronica Inf. e Sistemistica, Bologna Univ., Italy
Abstract :
A simple model of the chemical acid-base regulation in blood is formulated and analysed. The model incorporates only two interacting buffers representing bicarbonate and non-bicarbonate (mainly hemoglobin and plasma proteins) buffers. The results obtained show that, in spite of its simplicity, this model represents accurately a large set of relationships between CO2 concentration and partial pressure, pH, base excess (BE) within the physiological range of variables
Keywords :
biocontrol; CO2; CO2 concentration; acid-base balance; base excess; bicarbonate buffers; blood; chemical acid-base regulation; chemical regulation; hemoglobin; interacting buffers; nonbicarbonate buffers; pH; partial pressure; physiological range of variables; plasma proteins; simple model; Blood; Chemical analysis; Control systems; Hydrogen; Medical control systems; Nonlinear equations; Plasma chemistry; Proteins; Respiratory system; Steady-state;
Conference_Titel :
Engineering in Medicine and Biology Society, 1994. Engineering Advances: New Opportunities for Biomedical Engineers. Proceedings of the 16th Annual International Conference of the IEEE
Conference_Location :
Baltimore, MD
Print_ISBN :
0-7803-2050-6
DOI :
10.1109/IEMBS.1994.415307
