Nonlinear dynamics analysis of heart rate variability signal based on entropies in hypertrophic cardiomyopathy patients

This work presents the analysis of Pattern, Shannon and Renyi entropies of the heart rate and RTend interval signals of hypertrophic cardiomyopathy patients with high and low risk of sudden cardiac death (group A and B). The results were compared with a group of healthy subjects (group C). Four-hour ECG data segments from the night were analyzed. Entropies were calculated in the four frequency bands: LF (0-0.07 Hz), MF (0.07-0.15 Hz), HF (0.15-0.45 Hz), and in the total frequency band (Tot). An exhaustive study of the parameters that characterize the entropies was done. The results for the Rtend signal show that significant differences between group A and groups B and C, are done to the components of the LF band (p(AB)=0.005 and p(AC)=0.002). As well, the statistical differences in group C compared with group B were present in the HF band of the RR signal (p(BC)=0.009)