The effect of anisotropic permeability on fluid flow and species transport within cortical bone

Author

Keanini, Russell G.

Author_Institution

Dept. of Mech. Eng. & Eng. Sci., North Carolina Univ., Charlotte, NC, USA

fYear

1994

fDate

1994

Firstpage

1148

Abstract

Investigates the effect of anisotropic permeability on fluid flow and passive non-diffusive species transport in cortical bone. A model is developed which focuses on flow and transport induced by a single blood vessel within a porous anisotropic matrix. Model predictions are found to be qualitatively consistent with experimental observations. More significantly, the model suggests that flow within the cortex can in some instances be determined by local permeability characteristics, independent of the local pressure (stress) gradient. This result challenges the notion that external stress alone determines in-bone flow characteristics

Keywords

permeability; anisotropic permeability effect; cortical bone; experimental observations; external stress; fluid flow; in-bone flow characteristics; local pressure gradient; model predictions; passive nondiffusive species transport; porous anisotropic matrix; single blood vessel; stress gradient; Anisotropic magnetoresistance; Blood vessels; Bones; Brain modeling; Fluid flow; Irrigation; Mechanical engineering; Permeability; Predictive models; Stress;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1994. Engineering Advances: New Opportunities for Biomedical Engineers. Proceedings of the 16th Annual International Conference of the IEEE

Conference_Location

Baltimore, MD

Print_ISBN

0-7803-2050-6

Type

conf

DOI

10.1109/IEMBS.1994.415366

Filename

415366