DocumentCode :
2378032
Title :
Temporal logics for phylogenetic analysis via model checking
Author :
Blanco, Roberto ; de Miguel Casado, Gregorio ; Requeno, José Ignacio ; Colom, José Manuel
Author_Institution :
Dept. of Comput. Sci. & Syst. Eng. (DIIS), Univ. de Zaragoza, Zaragoza, Spain
fYear :
2010
fDate :
18-18 Dec. 2010
Firstpage :
152
Lastpage :
157
Abstract :
The need for general-purpose algorithms for the study of biological properties in phylogenetics motivates the research in formal verification frameworks so that researchers can focus their efforts exclusively on evolution modelling and property specification. To this end, model checking, a mature automated verification technique from computer science, is proposed for phylogenetic analysis. Three cornerstones found our approach: modelling evolution dynamics with transition systems; specifying phylogenetic properties using temporal logic formulae; and verifying the latter by means of automated computer tools. As prominent advantages stemming of studying phylogenetic properties with this approach, different models of evolution can be considered, complex properties can be specified as the logical composition of others, and the refinement of unfulfilled properties as well as the discovery of new ones can be undertaken by exploiting the verification results.
Keywords :
DNA; bioinformatics; data analysis; evolution (biological); genetics; genomics; molecular biophysics; temporal logic; DNA sequence; automated verification technique; data analysis; evolution dynamics; general-purpose algorithm; phylogenetic analysis; temporal logic formulae; formal verification; model checking; phylogenetic analysis; temporal logic;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Bioinformatics and Biomedicine Workshops (BIBMW), 2010 IEEE International Conference on
Conference_Location :
Hong, Kong
Print_ISBN :
978-1-4244-8303-7
Electronic_ISBN :
978-1-4244-8304-4
Type :
conf
DOI :
10.1109/BIBMW.2010.5703790
Filename :
5703790
Link To Document :
بازگشت