Title :
A model of sustained propagation in a 20-cell ring of Purkinje tissue
Author :
Papazoglou, Alexandra A. ; Barr, Roger C.
Author_Institution :
Dept. of Biomed. Eng., Duke Univ., Durham, NC, USA
Abstract :
Sustained and stable propagation was simulated in a ring of 20 cardiac cells with DiFrancesco-Noble membrane kinetics and connected with elevated junction resistances. The action potential propagated around the ring at least three times with no noticable change in the action potential shape in about 2.32 sec each time, or 0.116 sec/cell. These results demonstrate a circuit of reentry at the cellular level
Keywords :
physiological models; 2.32 s; 20-cell ring; DiFrancesco-Noble membrane kinetics; Purkinje tissue; action potential propagation; cardiac tissue ring; junction resistance; reentry circuit; sustained propagation model; Biomedical engineering; Biomembranes; Circuits; Conductivity; Electric resistance; Geometry; Immune system; Kinetic theory; Shape; Solid modeling;
Conference_Titel :
Engineering in Medicine and Biology Society, 1994. Engineering Advances: New Opportunities for Biomedical Engineers. Proceedings of the 16th Annual International Conference of the IEEE
Conference_Location :
Baltimore, MD
Print_ISBN :
0-7803-2050-6
DOI :
10.1109/IEMBS.1994.415384
