DocumentCode
2380452
Title
A new evaluation measure of diagnostic tests based on modified area under the receiver operating characteristic curve
Author
Yu, Wenbao ; Park, Eunsik ; Chang, Yuan-chin
Author_Institution
Dept. of Stat., Chonnam Nat. Univ., Gwangju, South Korea
fYear
2010
fDate
18-18 Dec. 2010
Firstpage
817
Lastpage
818
Abstract
In this paper, a new diagnostic/classification measure based on modified AUC (MAUC) is proposed. By this measure, we penalize the margin of features between diseased and non-diseased groups in AUC. It´s threshold independent, and under normal distribution assumption, we can prove that higher MAUC always means higher PAUC (within relatively low FPR) when AUCs are close to each other. Our simulations and experiment about prostate cancer MS data can also help to demonstrate it.
Keywords
biological organs; biomedical measurement; cancer; data analysis; medical diagnostic computing; patient diagnosis; sensitivity analysis; biomedical measurement; diagnostic tests; disease; modified area under ROC curves; normal distribution; prostate cancer data; receiver operating characteristic analysis; AUC; FPR; MAUC; PAUC; diagnostic; prostate cancer MS data;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and Biomedicine Workshops (BIBMW), 2010 IEEE International Conference on
Conference_Location
Hong, Kong
Print_ISBN
978-1-4244-8303-7
Electronic_ISBN
978-1-4244-8304-4
Type
conf
DOI
10.1109/BIBMW.2010.5703923
Filename
5703923
Link To Document