Functional MRI study of brain function under resting and activated states

Author

Chen, Wei ; Liu, Xiao ; Zhu, Xiao-Hong ; Zhang, Nanyin

Author_Institution

Dept. of Radiol., Univ. of Minnesota, Minneapolis, MN, USA

fYear

2009

fDate

3-6 Sept. 2009

Firstpage

4061

Lastpage

4063

Abstract

Numerous magnetic resonance imaging (MRI) techniques have been developed with various imaging contrasts, which can be tightly linked to brain functions, electrophysiology and diseases. Recent MRI technology developments have resulted in several important functional MRI (fMRI) methods based on the blood oxygenation level dependent (BOLD) contrast. These fMRI methods have been applied to mapping brain activation in laminar level as well functional connectivity network in a resting brain. We have found a strong correlation between the spontaneous brain activity and BOLD fluctuation indicating a tight neurovascular relation.

Keywords

bioelectric phenomena; biomedical MRI; blood vessels; brain; diseases; neural nets; neurophysiology; BOLD fluctuation; activated states; blood oxygenation level-dependent contrast; brain activation mapping; brain function; diseases; electrophysiology; functional MRI method; functional connectivity network; laminar level; magnetic resonance imaging techniques; resting states; spontaneous brain activity; tight neurovascular relation; Animals; Brain; Brain Mapping; Cats; Computer Simulation; Diagnostic Imaging; Humans; Magnetic Resonance Imaging; Models, Neurological; Nerve Net; Oxygen; Rats;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE

Conference_Location

Minneapolis, MN

ISSN

1557-170X

Print_ISBN

978-1-4244-3296-7

Electronic_ISBN

1557-170X

Type

conf

DOI

10.1109/IEMBS.2009.5333175

Filename

5333175