• DocumentCode
    2388737
  • Title

    Electrical modeling of a biochip for genetic manipulation of single cells

  • Author

    Bandiera, L. ; Borgo, M. ; Cellere, G. ; Toni, A. De ; Santoni, L. ; Bersani, C. ; Paccagnella, A.

  • Author_Institution
    Padova Univ.
  • fYear
    2006
  • fDate
    11-13 Dec. 2006
  • Firstpage
    1
  • Lastpage
    4
  • Abstract
    Electroporation is a widely used technique which allows introducing into cultured cells molecules which won´t enter in naturally because of the high selectivity of the cell membrane (this is called transfection). We are presenting in this paper a biochip comprising an array of microelectrodes which can be used to electroporate single cells instead than the large number of cells customarily treated with commonly used transfection techniques. In particular, we are dealing with electrical measurements of the biochip electrodes and with an accurate equivalent model
  • Keywords
    biomedical electrodes; biomolecular electronics; cellular biophysics; microelectrodes; biochip electrodes; cell membrane; cultured cell molecules; electrical measurements; electrical modeling; electroporation; genetic manipulation; microelectrodes; transfection techniques; Biomembranes; Cells (biology); Chemicals; DNA; Electrodes; Fluorescence; Frequency; Genetics; Protocols; Voltage;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Electron Devices Meeting, 2006. IEDM '06. International
  • Conference_Location
    San Francisco, CA
  • Print_ISBN
    1-4244-0438-X
  • Electronic_ISBN
    1-4244-0439-8
  • Type

    conf

  • DOI
    10.1109/IEDM.2006.346888
  • Filename
    4154307