DocumentCode :
2388737
Title :
Electrical modeling of a biochip for genetic manipulation of single cells
Author :
Bandiera, L. ; Borgo, M. ; Cellere, G. ; Toni, A. De ; Santoni, L. ; Bersani, C. ; Paccagnella, A.
Author_Institution :
Padova Univ.
fYear :
2006
fDate :
11-13 Dec. 2006
Firstpage :
1
Lastpage :
4
Abstract :
Electroporation is a widely used technique which allows introducing into cultured cells molecules which won´t enter in naturally because of the high selectivity of the cell membrane (this is called transfection). We are presenting in this paper a biochip comprising an array of microelectrodes which can be used to electroporate single cells instead than the large number of cells customarily treated with commonly used transfection techniques. In particular, we are dealing with electrical measurements of the biochip electrodes and with an accurate equivalent model
Keywords :
biomedical electrodes; biomolecular electronics; cellular biophysics; microelectrodes; biochip electrodes; cell membrane; cultured cell molecules; electrical measurements; electrical modeling; electroporation; genetic manipulation; microelectrodes; transfection techniques; Biomembranes; Cells (biology); Chemicals; DNA; Electrodes; Fluorescence; Frequency; Genetics; Protocols; Voltage;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Electron Devices Meeting, 2006. IEDM '06. International
Conference_Location :
San Francisco, CA
Print_ISBN :
1-4244-0438-X
Electronic_ISBN :
1-4244-0439-8
Type :
conf
DOI :
10.1109/IEDM.2006.346888
Filename :
4154307
Link To Document :
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