• DocumentCode
    238902
  • Title

    An examination of synchronisation in Artificial Gene Regulatory Networks

  • Author

    Byrne, James ; Nicolau, Miguel ; Brabazon, Anthony ; O´Neill, Maire

  • fYear
    2014
  • fDate
    6-11 July 2014
  • Firstpage
    2764
  • Lastpage
    2769
  • Abstract
    An Artificial Genetic Regulatory Network (GRN) is a model of the gene expression regulation mechanism in biological organisms. It is a dynamical system that is capable of mimicking non-linear time series. The GRN was adapted to allow for input and output so that the system´s rich dynamics could be used for dynamic problem solving. In order for the GRN to be embedded in the environment, the time scale of the physical system has to be mapped to that of the GRN and so a synchronisation process was introduced. This work examines the impact of different synchronisation intervals and how they effect the overall performance of the GRN. A variable synchronisation step that stops once the system has stabilised is also explored as a mechanism for automatically choosing the interval size.
  • Keywords
    biology; molecular biophysics; synchronisation; time series; GRN; artificial gene regulatory networks; biological organisms; gene expression regulation mechanism; nonlinear time series; synchronisation intervals; variable synchronisation step; Bioinformatics; Biological system modeling; Evolutionary computation; Genomics; Mathematical model; Proteins; Synchronization;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Evolutionary Computation (CEC), 2014 IEEE Congress on
  • Conference_Location
    Beijing
  • Print_ISBN
    978-1-4799-6626-4
  • Type

    conf

  • DOI
    10.1109/CEC.2014.6900385
  • Filename
    6900385