DocumentCode :
238902
Title :
An examination of synchronisation in Artificial Gene Regulatory Networks
Author :
Byrne, James ; Nicolau, Miguel ; Brabazon, Anthony ; O´Neill, Maire
fYear :
2014
fDate :
6-11 July 2014
Firstpage :
2764
Lastpage :
2769
Abstract :
An Artificial Genetic Regulatory Network (GRN) is a model of the gene expression regulation mechanism in biological organisms. It is a dynamical system that is capable of mimicking non-linear time series. The GRN was adapted to allow for input and output so that the system´s rich dynamics could be used for dynamic problem solving. In order for the GRN to be embedded in the environment, the time scale of the physical system has to be mapped to that of the GRN and so a synchronisation process was introduced. This work examines the impact of different synchronisation intervals and how they effect the overall performance of the GRN. A variable synchronisation step that stops once the system has stabilised is also explored as a mechanism for automatically choosing the interval size.
Keywords :
biology; molecular biophysics; synchronisation; time series; GRN; artificial gene regulatory networks; biological organisms; gene expression regulation mechanism; nonlinear time series; synchronisation intervals; variable synchronisation step; Bioinformatics; Biological system modeling; Evolutionary computation; Genomics; Mathematical model; Proteins; Synchronization;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Evolutionary Computation (CEC), 2014 IEEE Congress on
Conference_Location :
Beijing
Print_ISBN :
978-1-4799-6626-4
Type :
conf
DOI :
10.1109/CEC.2014.6900385
Filename :
6900385
Link To Document :
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