DocumentCode
238902
Title
An examination of synchronisation in Artificial Gene Regulatory Networks
Author
Byrne, James ; Nicolau, Miguel ; Brabazon, Anthony ; O´Neill, Maire
fYear
2014
fDate
6-11 July 2014
Firstpage
2764
Lastpage
2769
Abstract
An Artificial Genetic Regulatory Network (GRN) is a model of the gene expression regulation mechanism in biological organisms. It is a dynamical system that is capable of mimicking non-linear time series. The GRN was adapted to allow for input and output so that the system´s rich dynamics could be used for dynamic problem solving. In order for the GRN to be embedded in the environment, the time scale of the physical system has to be mapped to that of the GRN and so a synchronisation process was introduced. This work examines the impact of different synchronisation intervals and how they effect the overall performance of the GRN. A variable synchronisation step that stops once the system has stabilised is also explored as a mechanism for automatically choosing the interval size.
Keywords
biology; molecular biophysics; synchronisation; time series; GRN; artificial gene regulatory networks; biological organisms; gene expression regulation mechanism; nonlinear time series; synchronisation intervals; variable synchronisation step; Bioinformatics; Biological system modeling; Evolutionary computation; Genomics; Mathematical model; Proteins; Synchronization;
fLanguage
English
Publisher
ieee
Conference_Titel
Evolutionary Computation (CEC), 2014 IEEE Congress on
Conference_Location
Beijing
Print_ISBN
978-1-4799-6626-4
Type
conf
DOI
10.1109/CEC.2014.6900385
Filename
6900385
Link To Document