Measurement of the attenuation coefficient for monodisperse populations of ultrasound contrast agents

In this paper, we describe a technique for producing populations of ultrasound contrast agents (UCA) with a narrow size distribution. Using acoustic techniques, we measure the frequency-dependent attenuation coefficient for suspensions of ultrasound contrast agents with varying size distributions, ranging from narrow to wide. Our results demonstrate that as the size distribution becomes more uniform, attenuation occurs within a narrow frequency range. Additionally, as the mean size decreases, the peak in the attenuation coefficient occurs at a higher frequency.