Title :
Light-controlled retinal stimulation on rabbit using CMOS-based flexible multi-chip stimulator
Author :
Tokuda, T. ; Takeuchi, Y. ; Noda, T. ; Sasagawa, K. ; Nishida, K. ; Kitaguchi, Y. ; Fujikado, T. ; Tano, Y. ; Ohta, J.
Author_Institution :
Nara Inst. Sci. & Technol., Ikoma, Japan
Abstract :
We implemented a light-sensing function on CMOS-based multi-chip stimulator for retinal prosthesis. Using the light-sensing circuitry attached to each stimulation electrode, the flexible multi-chip stimulator is capable of image-based patterned stimulation. We verified the function of the light-controlled decision based on the light intensity measured just beside the stimulation site. We also experimentally demonstrated in vivo retinal stimulation on rabbit´s retina with light-controlled decision. The result of the present work is a simplified demonstration for the concept of retinal prosthesis with on-site imaging.
Keywords :
CMOS integrated circuits; biomedical electrodes; biomedical electronics; eye; flexible electronics; neurophysiology; prosthetics; CMOS-based flexible multichip stimulator; image-based patterned stimulation; light intensity measurement; light-controlled decision; light-controlled retinal stimulation electrode; light-sensing circuitry; light-sensing function; on-site imaging; retinal prosthesis technology; Electric Stimulation Therapy; Electrodes, Implanted; Equipment Design; Equipment Failure Analysis; Image Interpretation, Computer-Assisted; Light; Photic Stimulation; Prostheses and Implants; Retina; Semiconductors; Signal Processing, Computer-Assisted;
Conference_Titel :
Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE
Conference_Location :
Minneapolis, MN
Print_ISBN :
978-1-4244-3296-7
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2009.5333809