Title :
μ-cell fatigue test
Author :
Fukui, Wataru ; Kaneko, Makoto ; Sakuma, Shinya ; Kawahara, Tomohiro ; Arai, Fumihito
Author_Institution :
Dept. of Mech. Eng., Osaka Univ., Suita, Japan
Abstract :
A new concept of μ-cell fatigue test is proposed. By reciprocating a cell across the throat of a micro channel repeatedly, the dynamic deformation behavior of the cell is measured. We define a new index of fatigue characteristics of cells as the number of reciprocatory motion leading to a prescribed recovery ratio. The test system is composed of a piezoelectric (PZT) actuator, a high speed vision sensor and a micro channel with a throat. Preliminary experiments were conducted by using Red Blood Cells (RBCs). The result suggested that the activation level of a cell can be evaluated based on its fatigue characteristics.
Keywords :
bioMEMS; biomechanics; blood; cellular biophysics; deformation; fatigue; fatigue testing; image sensors; microchannel flow; piezoelectric actuators; recovery; μ-cell fatigue test; dynamic deformation; high speed vision sensor; microchannel; piezoelectric actuator; reciprocatory motion; recovery ratio; red blood cells; Actuators; Cameras; Diseases; Fatigue; Indexes; Microchannel; Sensors;
Conference_Titel :
Robotics and Automation (ICRA), 2012 IEEE International Conference on
Conference_Location :
Saint Paul, MN
Print_ISBN :
978-1-4673-1403-9
Electronic_ISBN :
1050-4729
DOI :
10.1109/ICRA.2012.6224856
