• DocumentCode
    2416591
  • Title

    Active CMOS Array for Electrochemical Sensing of Biomolecules

  • Author

    Levine, Peter M. ; Gong, Ping ; Shepard, Kenneth L. ; Levicky, Rastislav

  • Author_Institution
    Columbia Univ., New York
  • fYear
    2007
  • fDate
    16-19 Sept. 2007
  • Firstpage
    825
  • Lastpage
    828
  • Abstract
    We describe the design of a 4times4 active sensor array for multiplexed electrochemical biomolecular detection in a 0.25-mum-CMOS process. Integrated potentiostats sense the current flowing through the on-chip Au electrodes that result from reactions occurring at the chip surface. Preliminary experimental results include cyclic voltammetry of several redox species and application to DNA probe coverage characterization.
  • Keywords
    CMOS integrated circuits; DNA; electrochemical electrodes; electrochemical sensors; gold; molecular biophysics; sensor arrays; Au; DNA probe; active CMOS array; active sensor array; biomolecular detection; biomolecules; cyclic voltammetry; electrochemical sensing; gold electrodes; integrated potentiostats; multiplexed electrochemical detection; size 0.25 mum; Biomedical measurements; CMOS process; Circuits; Current measurement; DNA; Electrodes; Molecular biophysics; Probes; Sensor arrays; Sensor phenomena and characterization;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Custom Integrated Circuits Conference, 2007. CICC '07. IEEE
  • Conference_Location
    San Jose, CA
  • Print_ISBN
    978-1-4244-1623-3
  • Electronic_ISBN
    978-1-4244-1623-3
  • Type

    conf

  • DOI
    10.1109/CICC.2007.4405855
  • Filename
    4405855