DocumentCode
2419970
Title
Fabrication of Microneedles
Author
Hsu, Chin-Chun ; Chen, Yu-Tang ; Tsai, Chieh-Hsiu ; Kang, Shung-Wen
Author_Institution
Dept. of Mech. & Electro-Mech. Eng., Tamkang Univ., Tamsui
fYear
2007
fDate
16-19 Jan. 2007
Firstpage
639
Lastpage
642
Abstract
This research paper was performed to study and utilizes two kinds of materials which match with two different fabrications in order to design an ideal shape of microneedles. The technology employs the polymer microneedles and the silicon microneedles with the height of 236 mum and 350 mum respectively. Moreover, the transdermal drug delivery investigation was conducted by using the fabricated samples to estimate the feasibility of the microneedles. Polymer microneedles were formed by molding the V-grooves structure on silicon wafer. The SU-8 negative photoresist was introduced for the subject structural material of the microneedles. Silicon microneedles were formed by KOH etching solution, solely depending on controlling etching time and the principle of fast-etching planes.
Keywords
drug delivery systems; etching; microfluidics; needles; photoresists; polymers; 236 micron; 350 micron; KOH etching solution; SU-8 negative photoresist; V-grooves structure; fast-etching planes; microneedle fabrication; photolithography; polymer microneedles; silicon microneedles; silicon wafer; transdermal drug delivery; Anisotropic magnetoresistance; Design engineering; Drugs; Fabrication; Microchannel; Micromechanical devices; Polymers; Resists; Shape; Silicon; Fast-etching planes; Microneedles; Photolithography; SU-8; V-groove;
fLanguage
English
Publisher
ieee
Conference_Titel
Nano/Micro Engineered and Molecular Systems, 2007. NEMS '07. 2nd IEEE International Conference on
Conference_Location
Bangkok
Print_ISBN
1-4244-0610-2
Type
conf
DOI
10.1109/NEMS.2007.352099
Filename
4160402
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