Title :
Development of a realistic head model for EEG event-detection and source localization in newborn infants
Author :
Despotovic, Ivana ; Deburchgraeve, Wouter ; Hallez, Hans ; Vansteenkiste, Ewout ; Philips, Wilfried
Author_Institution :
Fac. of Electr. Eng., Ghent Univ., Ghent, Belgium
Abstract :
In this work we present an integrated method for electroencephalography (EEG) source localization in newborn infants, based on a realistic head model. To build a realistic head model we propose an interactive hybrid segmentation method for T1 magnetic resonance images (MRI), consisting of active contours, fuzzy c-means (FCM) clustering and mathematical morphology. Subsequently, we solve the localization problem using a spike train detection algorithm and an algorithm that deals with the forward and inverse problem. The performance of this fused method indicates that our realistic head model is suitable for the accurate localization of the EEG activity. We will present both initial qualitative and quantitative results.
Keywords :
biomedical MRI; electroencephalography; image segmentation; medical image processing; medical signal detection; physiological models; EEG; active contours; electroencephalography; event detection; forward problem; fuzzy c-means clustering; interactive hybrid segmentation; inverse problem; magnetic resonance imaging; mathematical morphology; newborn infants; realistic head model; source localization; spike train detection algorithm; Algorithms; Brain; Brain Mapping; Cluster Analysis; Electroencephalography; Fuzzy Logic; Head; Humans; Infant, Newborn; Magnetic Resonance Imaging; Models, Statistical; Models, Theoretical; Phantoms, Imaging;
Conference_Titel :
Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE
Conference_Location :
Minneapolis, MN
Print_ISBN :
978-1-4244-3296-7
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2009.5335052