Overview of the optofluidic ring resonator: A versatile platform for label-free biological and chemical sensing

Author

Suter, Jonathan D. ; Fan, Xudong

Author_Institution

Dept. of Biol. Eng., Univ. of Missouri, Columbia, MO, USA

fYear

2009

fDate

3-6 Sept. 2009

Firstpage

1042

Lastpage

1044

Abstract

Highly sensitive detection of biological and chemical analytes has significant importance within medical science, environmental monitoring, food quality, national security and defense. The opto-fluidic ring resonator (OFRR) is a relatively new solution for label-free optical sensing that is compatible with a versatile range of analytes. A capillary-based platform, the OFRR supports whispering gallery modes within its circular cross-section and conducts evanescent sensing within its hollow core. Herein, we provide an overview of the basic operation principles of the OFRR and some examples of its most important applications, including the detection of proteins, virus, DNA molecules, whole cells, vapors and pesticides.

Keywords

biosensors; chemical sensors; fibre optic sensors; optical resonators; whispering gallery modes; DNA molecules; capillary-based platform; circular cross-section; environmental monitoring; evanescent sensing; food quality; high-sensitive detection; label-free biological sensing; label-free chemical sensing; medical science; national security; optical sensing; optofluidic ring resonator; pesticides; protein detection; vapor detection; virus detection; whispering gallery modes; whole cell detection; Biopolymers; Biosensing Techniques; Equipment Design; Equipment Failure Analysis; Fiber Optic Technology; Flow Injection Analysis; Light; Microfluidic Analytical Techniques; Refractometry; Reproducibility of Results; Scattering, Radiation; Sensitivity and Specificity; Staining and Labeling; Transducers;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE

Conference_Location

Minneapolis, MN

ISSN

1557-170X

Print_ISBN

978-1-4244-3296-7

Electronic_ISBN

1557-170X

Type

conf

DOI

10.1109/IEMBS.2009.5335153

Filename

5335153