Title :
Dried nanoparticle label reagents for microfluidic immunoassays
Author :
Kreutzer, Joose M. ; Lehtinen, Pekka ; Kallio, Pasi J. ; Välimaa, Lasse
Author_Institution :
Dept. of Autom. Sci. & Eng., Tampere Univ. of Technol., Tampere, Finland
Abstract :
In this paper, we demonstrate and analyze the solubility and distribution of dried europium(III)-chelate dyed nanoparticles in mini channels of milled polystyrene (PS) cartridges. The particular objective for the study is to measure quantitatively the efficiency of the resuspension of dried nanoparticles from the surface of PS channels and to determine the homogeneity of the solute particles in a reaction chamber considering also the incubation time.
Keywords :
bioMEMS; drying; dyes; europium; microchannel flow; microfabrication; milling; nanoparticles; polymers; solubility; suspensions; dried europium(III)-chelate dyed nanoparticles; homogeneity; incubation time; microfluidic immunoassays; milled polystyrene cartridges; milling; nanoparticle label reagents; reaction chamber; resuspension; solubility; solute particles; dry chemistry; homogeneity; immunoassay; nanoparticle; passive valve; solubility;
Conference_Titel :
Nano/Micro Engineered and Molecular Systems (NEMS), 2010 5th IEEE International Conference on
Conference_Location :
Xiamen
Print_ISBN :
978-1-4244-6543-9
DOI :
10.1109/NEMS.2010.5592194