DNA-grafted-polymer mediated self-assembly of micro components

Author

Lopez, Guillermo ; Tanemura, Tomoki ; Sato, Ryo ; Saeki, Takahiro ; Hirai, Yoshikazu ; Sugano, Koji ; Tsuchiya, Toshiyuki ; Tabata, Osamu ; Fujita, Masahiro ; Maeda, Mizuo

Author_Institution

Dept. of Micro Eng., Kyoto Univ., Kyoto, Japan

fYear

2010

fDate

20-23 Jan. 2010

Firstpage

245

Lastpage

249

Abstract

Systematic experiments of DNA mediated sequential and selective self-assembly of 5 × 5 (μm²) silicon micro-components to a substrate using DNA-grafted-polymers as flexible binding spacers were carried out for the first time. The surfaces of the micro-components and sites on the substrate were modified by the same 30-mers single-stranded-DNA (ssDNA). The complementary ssDNA was grafted to a polymer to form DNA-grafted-polymer. Four types of DNA-grafted-polymer with two different ssDNA hybridization lengths and two different ssDNA fractions were prepared. From the measured time dependence of the number of self-assembled micro-components on the sites, the DNA-grafted-polymer technique proved to greatly enhance the assembly yield and time compared to direct self-assembly between micro-components and sites.

Keywords

DNA; micromechanical devices; self-assembly; DNA-grafted-polymer mediated self-assembly; assembly yield; flexible binding spacers; selective self-assembly; sequential self-assembly; Assembly; DNA; DNA-Grafted-Polymer; Hybridization; MEMS; Microassembly; Nanotechnology; Polymer; Selective; Self-Assembly; Sequential;

fLanguage

English

Publisher

ieee

Conference_Titel

Nano/Micro Engineered and Molecular Systems (NEMS), 2010 5th IEEE International Conference on

Conference_Location

Xiamen

Print_ISBN

978-1-4244-6543-9

Type

conf

DOI

10.1109/NEMS.2010.5592199

Filename

5592199