Title :
Microscopy of gold nanoshells in tumors using two-photon induced photoluminescence
Author :
Park, J. ; Estrada, A. ; Diagaradjane, P. ; Sharp, K. ; Sang, K. ; Schwartz, J.A. ; Coleman, C. ; Payne, J.D. ; Dunn, A.K. ; Krishnan, S. ; Tunnell, J.W.
Author_Institution :
Dept. of Biomed. Eng., Univ. of Texas at Austin, Austin, TX
Abstract :
We report the nonlinear photo-physical properties of silica/gold nanoshells (NS) and demonstrate their application as biological imaging agents. We present images of the microscopic distribution of nanoshells in murine tumors using NIR laser scanning multi-photon microscopy.
Keywords :
gold; nanobiotechnology; optical microscopy; photoluminescence; tumours; two-photon processes; Au; NIR laser scanning multiphoton microscopy; biological imaging agents; gold nanoshells; tumors; two-photon induced photoluminescence; Gold; Laser excitation; Luminescence; Microscopy; Nanobioscience; Neoplasms; Optical imaging; Optical scattering; Photoluminescence; Sea surface; Optical imaging; contrast agents; gold nanoparticles; nonlinear imaging;
Conference_Titel :
IEEE/LEOS Summer Topical Meetings, 2008 Digest of the
Conference_Location :
Acapulco
Print_ISBN :
978-1-4244-1925-8
Electronic_ISBN :
1099-4742
DOI :
10.1109/LEOSST.2008.4590494