DocumentCode
2433299
Title
Light image patterned molecular delivery into live cells using gold particle coated substrate
Author
Wu, Ting-Hsiang ; Kalim, Sheraz ; Callahan, Caitlin ; Teitell, Michael ; Chiou, Pei-Yu
Author_Institution
Dept. of Electr. Eng., Univ. of California, Los Angeles, CA
fYear
2008
fDate
21-23 July 2008
Firstpage
195
Lastpage
196
Abstract
Light-patterned molecular delivery into cells is demonstrated by pulsed laser irradiation of gold particles immobilized on the substrate below a cell monolayer. Molecular delivery is verified by observing the uptake of membrane-impermeable fluorescent dye.
Keywords
biological effects of laser radiation; biological techniques; cellular effects of radiation; cellular transport; dyes; fluorescence; genetics; gold; laser beam applications; molecular biophysics; monolayers; Au; cell monolayer; gold particle coated substrate; gold particles immobilization; light image patterned molecular delivery; live cells; membrane-impermeable fluorescent dye uptake; optoporation; pulsed laser irradiation; Biomembranes; Cells (biology); Explosives; Fluorescence; Gold; Large-scale systems; Laser beams; Optical control; Optical pulses; Ultrafast optics;
fLanguage
English
Publisher
ieee
Conference_Titel
IEEE/LEOS Summer Topical Meetings, 2008 Digest of the
Conference_Location
Acapulco
ISSN
1099-4742
Print_ISBN
978-1-4244-1925-8
Electronic_ISBN
1099-4742
Type
conf
DOI
10.1109/LEOSST.2008.4590556
Filename
4590556
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