Title :
Design and analysis of SOI based biosensor with integrated optic readout
Author :
Malathi, Sathish ; Rani, K.R. ; Srinivas, T.
Author_Institution :
Dept. of Electr. & Commun. Eng., Indian Inst. of Sci., Bangalore, India
Abstract :
In this paper we have proposed and analyzed a novel integrated optic racetrack resonator based biosensor. The device is capable of distinguishing compressive and tensile stresses on a cantilever due to conformational changes of protein. We have considered Bovine Serum Albumin (BSA) and Immunoglobulin G (IgG). The change of surface stress upon adsorption of IgG is compressive and of BSA is tensile. When the biomolecules adhere to the device surface, due to photo elastic effect the effective refractive index and length of racetrack resonator change. Our simulation results show that the resonant wavelength shifts by 0.3196 × 10-3 nm/ με which is a measure of surface stress.
Keywords :
bioMEMS; biological techniques; cantilevers; integrated optics; micro-optomechanical devices; microsensors; molecular biophysics; molecular configurations; optical resonators; optical sensors; proteins; refractive index; silicon-on-insulator; BSA; IgG; Si-Jk; adsorption; biomolecules; biosensor; bovine serum albumin; cantilever; compressive stress; conformation; immunoglobulin; integrated optic racetrack resonator; integrated optic readout; photoelastic effect; protein; refractive index; surface stress; tensile stress; Biomedical optical imaging; Optical ring resonators; Optical sensors; Optical variables control; Optical waveguides;
Conference_Titel :
Computing Communication and Networking Technologies (ICCCNT), 2010 International Conference on
Conference_Location :
Karur
Print_ISBN :
978-1-4244-6591-0
DOI :
10.1109/ICCCNT.2010.5592574
