Title :
The cooperative transport mechine of protein motors under the electrostatic interaction
Author_Institution :
Sci. Educ. Dept., Beijing Inst. of Graphic Commun., Beijing, China
Abstract :
Kinesin transports cargos along the microtubule and myosin along the actin. The experiment finds that when kinesin-2 and myosin V transport a same cargo together, they act as tethers to enhance each others´ processivity because of the electrostatic interaction between them and the tracks. Here, on the basis of the experiment, the electrostatic interaction between the protein and the track is considered, and the effects of the electrostatic interaction, the rate of dissociation, and the rate of re-combining on the run length of the motor respectively are studied. The results explain qualitatively the experimental phenomena.
Keywords :
biochemistry; biotransport; dissociation; molecular biophysics; physiological models; proteins; actin; cooperative transport machine; dissociation; electrostatic interaction; kinesin; microtubule; myosin; protein motors; recombination rate; Electrostatics; Equations; Load modeling; Mathematical model; Presence network agents; Proteins; Tracking; electrostatic interaction; protein motor; the cooperative transport;
Conference_Titel :
Remote Sensing, Environment and Transportation Engineering (RSETE), 2011 International Conference on
Conference_Location :
Nanjing
Print_ISBN :
978-1-4244-9172-8
DOI :
10.1109/RSETE.2011.5964186