Design Study for a Cellular Culture Bioreactor Coupled with a Magnetic Stimulation System

This article presents a design study performed to integrate a cellular culture bioreactor along with an external magnetic stimulation system, aimed at creating ideal environmental conditions that allow for cellular culture and cellular tissue growth to take place in three dimensions, under a sterile environment favorable for the development of bioorganic grafts which have been exposed to controlled electromagnetic fields. The different systems that have been designed and constructed are described along with their particular characteristics and all general considerations that were taken into account during the design process are presented, as well as the main variables that must be considered during implementation in order to guarantee constant and adequate function of the integrated systems, as well as reproducible results.