Title :
Laser scanning calibration for porous silicon substrate useful in microarray applications
Author :
Simion, Monica ; Kleps, Irina ; Ruta, Lavinia ; Lazar, Lucia ; Bragaru, Adina ; Miu, Mihaela ; Baciu, Ion
Author_Institution :
Nat. Inst. for R&D in Microtechnol. (IMT Bucharest), Bucharest, Romania
Abstract :
This paper reviews some of the most important technical aspects related to the reader system used in microarray technology straightening the importance of the working conditions for the accuracy of the data as well as the measures which should be considered for optimization of the detection process with exemplification on porous substrate printed with bovine serum albumin (BSA) labelled with Cy3 fluorophore.
Keywords :
biosensors; calibration; laser applications in medicine; optimisation; organic compounds; silicon; Cy3 fluorophore; bovine serum albumin; laser scanning calibration; microarray applications; optimization; porous silicon substrate; Calibration; Chemical lasers; Chemical technology; Chemistry; Fluorescence; Gold; Image converters; Proteins; Silicon; Surface emitting lasers; biology; laser methods in chemistry; medicine; microarray technology; protein immobilisation;
Conference_Titel :
Semiconductor Conference, 2009. CAS 2009. International
Conference_Location :
Sinaia
Print_ISBN :
978-1-4244-4413-7
DOI :
10.1109/SMICND.2009.5336585