• DocumentCode
    2450886
  • Title

    Efficient and scalable parallel reconstruction of sibling relationships from genetic data in wild populations

  • Author

    Sheikh, Saad ; Khokhar, Ashfaq ; Berger-Wolf, Tanya

  • Author_Institution
    Dept. of Comput. Sci., Univ. of Illinois at Chicago, Chicago, IL, USA
  • fYear
    2010
  • fDate
    19-23 April 2010
  • Firstpage
    1
  • Lastpage
    8
  • Abstract
    Wild populations of organism are often difficult to study in their natural settings. Often, it is possible to infer mating information about these species by genotyping the offspring and using the genetic information to infer sibling, and other kinship, relationships. While sibling reconstruction has been studied for a long time, none of the existing approaches have targeted scalability. In this paper, we introduce the first parallel approach to reconstructing sibling relationships from microsatellite markers. We use both functional and data domain decomposition to break down the problem and argue that this approach can be applied to other problems where columns are independent and simple constraint-based enumeration is required. We discuss algorithmic and implementation choices and their effects on results. We show that our approach is highly efficient and scalable.
  • Keywords
    biology computing; genetics; parallel processing; constraint-based enumeration; data domain decomposition; functional decomposition; genetic data; genetic information; microsatellite markers; parallel reconstruction; sibling reconstruction; sibling relationship; wild population;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Parallel & Distributed Processing, Workshops and Phd Forum (IPDPSW), 2010 IEEE International Symposium on
  • Conference_Location
    Atlanta, GA
  • Print_ISBN
    978-1-4244-6533-0
  • Type

    conf

  • DOI
    10.1109/IPDPSW.2010.5470892
  • Filename
    5470892