DocumentCode :
2460076
Title :
Three-dimensional Vision-based Nail-fold Morphological and Hemodynamic Analysis
Author :
Lo, Lun-chien ; Chiang, John Y. ; Cai, Yu-shan
Author_Institution :
Dept. of Traditional Chinese Med., Changhua Christian Hosp., Changhua, Taiwan
fYear :
2011
fDate :
24-26 Oct. 2011
Firstpage :
44
Lastpage :
51
Abstract :
In this paper, a Three-dimensional Vision-based Nail-fold Morphological and Hemodynamic Analysis (TVNMHA) is proposed to automatically extract morphological/hemodynamic features from an image sequence, reconstruct the corresponding three-dimensional vacular tubular models, and visualize the dynamic blood flow in the model constructed. The morphological features extracted include number, density, width/height, width of the curved segment, arteriolar limb caliber, curved segment caliber, venular limb caliber, blood color and tortuosity of capillaries. The corresponding pathological information derived has a spatial precision accurate up to 1.6μm. TVNMHA also employs optical flow method (OFM) to measure the velocity of the flowing plasma gaps between two consecutive frames with an error ≈10-32μm/sec [1]. The laser Doppler velocimetry is a common tool employed in measuring capillary with larger diameter (is about ≈500μm). The average velocity of an area measured comes with an error around ≈100μm/sec [2], much higher than that of TVNMHA. TVNMHA can separately derive velocities for each capillaries within the whole microscopic range and obtain diversified morphological/hemodynamic features of capillaries with a low-cost equipment setup.
Keywords :
Doppler measurement; biomedical optical imaging; capillarity; feature extraction; flow visualisation; haemodynamics; haemorheology; image reconstruction; image segmentation; image sequences; laser velocimetry; medical image processing; physiological models; 3D vision-based nail-fold morphological analysis; arteriolar limb caliber; blood color; capillary tortuosity; curved segment caliber; dynamic blood flow; feature extraction; flow visualization; hemodynamic analysis; image reconstruction; image sequence; laser Doppler velocimetry; low-cost equipment setup; optical flow method; pathological information; plasma gaps; three-dimensional vacular tubular models; venular limb caliber; Feature extraction; Hemodynamics; Image segmentation; Microscopy; Skeleton; Velocity measurement; 3D visualization; finger nail-fold morphological/hemodynamic analysis; microcirculation; three-dimensional capillary reconstruction;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Bioinformatics and Bioengineering (BIBE), 2011 IEEE 11th International Conference on
Conference_Location :
Taichung
Print_ISBN :
978-1-61284-975-1
Type :
conf
DOI :
10.1109/BIBE.2011.14
Filename :
6089806
Link To Document :
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