DocumentCode
2460536
Title
Molecular Modeling Studies of AmpR Mediated AmpC ß-Lactamase Repression
Author
Hecht, David A. ; Wang, Charles C N ; Hu, Rouh-Mei ; Tsai, Jeffrey J P
Author_Institution
Dept. of Bioinf., Asia Univ., Taichung, Taiwan
fYear
2011
fDate
24-26 Oct. 2011
Firstpage
195
Lastpage
200
Abstract
Molecular modeling and in silico docking experiments were performed in order to study the mechanism of action of AmpC beta-Lactamase repression via AmpR binding of UDP-MurNAc-L-Ala-D-gamma-Glu-Meso-2,6-Diaminopimelete-D-Ala-D-Ala.
Keywords
biochemistry; enzymes; molecular biophysics; AmpR binding; AmpR mediated AmpC β-lactamase repression; UDP-MurNAc-L-Ala-D-γGlu-meso-2,6-diaminopimelete-D-Ala-D-Ala; in-silico docking experiment; molecular modeling; Antibiotics; Compounds; Crystals; Gold; Immune system; Libraries; Proteins; ß-Lactamase; AmpC; AmpR; MRSA; antibiotic resistance; docking;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and Bioengineering (BIBE), 2011 IEEE 11th International Conference on
Conference_Location
Taichung
Print_ISBN
978-1-61284-975-1
Type
conf
DOI
10.1109/BIBE.2011.37
Filename
6089828
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