Title :
Tracking the 3-Base Periodicity of Protein-Coding Regions by the Nonlinear Tracking-Differentiator
Author :
Yin, Changchuan ; Yoo, Dongchul ; Yau, Stephen S -T
Author_Institution :
Dept. of Math., Stat. & Comput. Sci., Illinois Univ., Chicago, IL
Abstract :
In this paper, a new algorithm to predict protein-coding regions by tracking the 3-base periodicity of DNA sequences is presented. A nonlinear tracking-differentiator (TD) is explored to generate smooth approximation of the trajectories of the 3-periodicity of DNA sequences and compute the derivatives, based on which protein-coding and non-coding regions can be identified. Case studies demonstrate that the nonlinear TD is an effective method to improve the accuracy of the gene finding algorithm
Keywords :
DNA; genetics; 3-base periodicity tracking; DNA sequences; nonlinear tracking-differentiator; protein-coding region prediction; Bioinformatics; Computer science; DNA; Genomics; Mathematics; Prediction algorithms; Proteins; Sequences; Statistics; Trajectory;
Conference_Titel :
Decision and Control, 2006 45th IEEE Conference on
Conference_Location :
San Diego, CA
Print_ISBN :
1-4244-0171-2
DOI :
10.1109/CDC.2006.377109
