CenterSurface model for 3D analysis of regional left ventricular function

The growing availability of surface reconstructions of the heart has increased interest in methods of quantitative analysis of left ventricular (LV) function in 3D. The authors are interested in transferring the advantages of the Centerline method from 2D to 3D. In the CenterSurface method, a medial surface is constructed between reconstructions of the endocardium at end diastole and end systole for wall motion analysis, and between the endocardial and epicardial surfaces for wall thickness. The measurement of motion or wall thickness is made perpendicular to the medial surface. The CenterSurface method will enable one to analyze regional LV wall motion or wall thickening in a uniform manner, independent of patient-to-patient differences in LV size and shape, and using data from any tomographic imaging modality