DocumentCode :
2468536
Title :
Intracoronary ultrasound plaque volume quantification
Author :
Dhawale, P.J. ; Rasheed, Q. ; Griffin, N. ; Wilson, D.L. ; Hodgson, J.McB.
Author_Institution :
Dept. of Biomed. Eng., Case Western Reserve Univ., Cleveland, OH, USA
fYear :
1993
fDate :
5-8 Sep 1993
Firstpage :
121
Lastpage :
124
Abstract :
An intracoronary ultrasound (ICUS) methodology for quantitative volumetric analysis of coronary atheroma was developed and validated. Sources of errors associated with volumetric ICUS were studied using computer simulations. These issues were addressed experimentally by implementing a data acquisition scheme to acquire calibrated, cardiac gated 3D data. A semi-automated segmentation scheme was developed to compute the plaque area which is enclosed between the luminal boundary and the media-adventitia interface. Volumetric validations were performed on phantoms resembling stenotic arteries. Multiple pull-backs were performed on the phantoms to assess reproducibility. Clinical applicability was assessed by quantifying plaque volumes in 4 patients before and after directional coronary atherectomy. It was found that ICUS has the accuracy and reproducibility required for performing quantitative volumetric analysis of coronary atheroma. Such volumetric analysis will help determine mechanisms of interventions and provide critical data needed for regression and restenosis trials
Keywords :
biomedical measurement; biomedical ultrasonics; cardiology; image segmentation; measurement errors; medical image processing; volume measurement; calibrated cardiac gated 3D data; computer simulations; coronary atheroma; data acquisition scheme; directional coronary atherectomy; intracoronary ultrasound plaque volume quantification; luminal boundary; media-adventitia interface; medical diagnostic imaging; multiple pull-backs; phantoms resembling stenotic arteries; restenosis trials; semiautomated segmentation scheme; Arteries; Catheters; Computational modeling; Computer simulation; Data acquisition; Image segmentation; Imaging phantoms; Reproducibility of results; Tomography; Ultrasonic imaging;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Computers in Cardiology 1993, Proceedings.
Conference_Location :
London
Print_ISBN :
0-8186-5470-8
Type :
conf
DOI :
10.1109/CIC.1993.378489
Filename :
378489
Link To Document :
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